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Allosteric substrate release by a sialic acid TRAP transporter substrate binding protein

Abstract The tripartite ATP-independent periplasmic (TRAP) transporters enable Vibrio cholerae and Haemophilus influenzae to acquire sialic acid, aiding their colonization of human hosts. This process depends on SiaP, a substrate-binding protein (SBP) that captures and delivers sialic acid to the tr...

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Xehetasun bibliografikoak
Egile Nagusiak: Niels Schneberger, Philipp Hendricks, Martin F. Peter, Erik Gehrke, Sophie C. Binder, Paul-Albert Koenig, Stephan Menzel, Gavin H. Thomas, Gregor Hagelueken
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2024-11-01
Saila:Communications Biology
Sarrera elektronikoa:https://doi.org/10.1038/s42003-024-07263-6
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