Deciphering the role of IGFBP5 in delaying fibrosis and sarcopenia in aging skeletal muscle: therapeutic implications and molecular mechanisms

IntroductionSarcopenia is a condition characterized by the loss of muscle fibers and excessive deposition of extracellular matrix proteins. The interplay between muscle atrophy and fibrosis is a central feature of sarcopenia. While the mechanisms underlying skeletal muscle aging and fibrosis remain...

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Үндсэн зохиолчид:	Luze Shi, Zheci Ding, Jiwu Chen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-03-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	skeletal muscle fibroblasts skeletal muscle fibrosis skeletal muscle aging fibrosis sarcopenia
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1557703/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!