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Characterization of cognitive decline in long-duration type 1 diabetes by cognitive, neuroimaging, and pathological examinations

BACKGROUND We aimed to characterize factors associated with the under-studied complication of cognitive decline in aging people with long-duration type 1 diabetes (T1D).METHODS Joslin “Medalists” (n = 222; T1D ≥ 50 years) underwent cognitive testing. Medalists (n = 52) and age-matched nondiabetic co...

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Principais autores: Hetal S. Shah, Matthew N. DeSalvo, Anastasia Haidar, Surya Vishva Teja Jangolla, Marc Gregory Yu, Rebecca S. Roque, Amanda Hayes, John Gauthier, Nolan Ziemniak, Elizabeth Viebranz, I-Hsien Wu, Kyoungmin Park, Ward Fickweiler, Tanvi J. Chokshi, Tashrif Billah, Lipeng Ning, Atif Adam, Jennifer K. Sun, Lloyd Paul Aiello, Yogesh Rathi, Mel B. Feany, George L. King
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2025-03-01
coleção:JCI Insight
Assuntos:
Aging
Endocrinology
Acesso em linha:https://doi.org/10.1172/jci.insight.180226
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