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Genetic Dissection of Femoral and Tibial Microarchitecture

ABSTRACT Our understanding of the genetic control of bone strength has relied mainly on estimates of bone mineral density. Here we have mapped genetic factors that influence femoral and tibial microarchitecture using high‐resolution x‐ray computed tomography (8‐μm isotropic voxels) across a family o...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lu Lu, Jinsong Huang, Fuyi Xu, Zhousheng Xiao, Jing Wang, Bing Zhang, Nicolae Valentin David, Danny Arends, Weikuan Gu, Cheryl Ackert‐Bicknell, Olivia L Sabik, Charles R Farber, Leigh Darryl Quarles, Robert W Williams
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019-12-01
Schriftenreihe:JBMR Plus
Schlagworte:
ANIMAL MODEL; CORTICAL BONE; GENE ONTOLOGY; GENOME‐WIDE ASSOCIATION STUDIES; IGNOROME; μCT; QUANTITATIVE TRAIT LOCUS; SEX DIFFERENCE; SYSTEMS GENETICS; TRABECULAR BONE
Online-Zugang:https://doi.org/10.1002/jbm4.10241
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