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Identification of gut dysbiosis in axial spondyloarthritis patients and improvement of experimental ankylosing spondyloarthritis by microbiome-derived butyrate with immune-modulating function

IntroductionDysbiosis is an environmental factor that affects the induction of axial spondyloarthritis (axSpA) pathogenesis. In the present study, we investigated differences in the gut microbiota of patients with axSpA and revealed an association between specific gut microbiota and their metabolite...

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Principais autores: Hong Ki Min, Hyun Sik Na, JooYeon Jhun, Seon-Yeong Lee, Sun Shim Choi, Go Eun Park, Jeong Su Lee, In Gyu Um, Seung Yoon Lee, Hochan Seo, Tae-Seop Shin, Yoon-Keun Kim, Jennifer Jooha Lee, Seung-Ki Kwok, Mi-La Cho, Sung-Hwan Park
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-04-01
coleção:Frontiers in Immunology
Assuntos:
spondyloarthropathies
dysbiosis
gastrointestinal microbiome
Faecalibacterium prausnitzii
butyrate
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1096565/full
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