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The Frequency of <i>DPYD</i> c.557A>G in the Dominican Population and Its Association with African Ancestry

<b>Background/Objectives:</b> Genetic polymorphism of the dihydropyrimidine dehydrogenase gene (<i>DPYD</i>) is responsible for the variability found in the metabolism of fluoropyrimidines such as 5-fluorouracil (5-FU), capecitabine, or tegafur. The <i>DPYD</i> genotype is linked to variability in e...

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Principais autores: Mariela Guevara, Carla González de la Cruz, Fernanda Rodrigues-Soares, Ernesto Rodríguez, Caíque Manóchio, Eva Peñas-Lledó, Pedro Dorado, Adrián LLerena
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-12-01
Serier:Pharmaceutics
Fag:
fluoropyrimidines
<i>DPYD</i>
cancer
African ancestry
pharmacogenetics
Online adgang:https://www.mdpi.com/1999-4923/17/1/8
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