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PXR and 4β-Hydroxycholesterol Axis and the Components of Metabolic Syndrome

Pregnane X receptor (PXR) activation has been found to regulate glucose and lipid metabolism and affect obesity in response to high-fat diets. PXR also modulates vascular tone. In fact, PXR appears to regulate multiple components of metabolic syndrome. In most cases, the effect of PXR action is harm...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Janne Hukkanen, Jukka Hakkola
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-11-01
Schriftenreihe:Cells
Schlagworte:
Online-Zugang:https://www.mdpi.com/2073-4409/9/11/2445
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