Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma.

Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we a...

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Principais autores:	Even H Rustad, Malin Hultcrantz, Venkata D Yellapantula, Theresia Akhlaghi, Caleb Ho, Maria E Arcila, Mikhail Roshal, Akshar Patel, Denise Chen, Sean M Devlin, Austin Jacobsen, Ying Huang, Jeffrey E Miller, Elli Papaemmanuil, Ola Landgren
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2019-01-01
叢編:	PLoS ONE
在線閱讀:	https://doi.org/10.1371/journal.pone.0211600
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