α-Glucosidase Inhibitors Based on Oleanolic Acid for the Treatment of Immunometabolic Disorders

Using oleanolic acid as a starting compound, a series of new oleanane-type triterpenic derivatives were synthesized via <i>O</i>-acylation (with nicotinic, isonicotinic, and methoxycinnamic acid acyl chlorides), <i>N</i>-amidation (with cyclic- or polyamines), the Mannich reaction (with secondary cy...

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Autors principals:	Anastasiya V. Petrova, Denis A. Babkov, Elmira F. Khusnutdinova, Irina P. Baikova, Oxana B. Kazakova, Elena V. Sokolova, Alexander A. Spasov
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-08-01
Col·lecció:	Applied Sciences
Matèries:	triterpenoids oleanolic acid indole Mannich reaction type 2 diabetes α-glucosidase inhibiting activity
Accés en línia:	https://www.mdpi.com/2076-3417/13/16/9269
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