Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans

Abstract Background African ancestry populations have the highest burden of stroke worldwide, yet the genetic basis of stroke in these populations is obscure. The Stroke Investigative Research and Educational Network (SIREN) is a multicenter study involving 16 sites in West Africa. We conducted the...

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Bibliografische gegevens

Hoofdauteurs:	Rufus O. Akinyemi, Hemant K. Tiwari, Vinodh Srinivasasainagendra, Onoja Akpa, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Godwin O. Osaigbovo, Olga A. Mamaeva, Brian A. Halloran, Joshua Akinyemi, Daniel Lackland, Olugbo Y. Obiabo, Taofik Sunmonu, Innocent I. Chukwuonye, Oyedunni Arulogun, Carolyn Jenkins, Abiodun Adeoye, Atinuke Agunloye, Okechukwu S. Ogah, Godwin Ogbole, Adekunle Fakunle, Ezinne Uvere, Motunrayo M. Coker, Akinkunmi Okekunle, Osahon Asowata, Samuel Diala, Mayowa Ogunronbi, Osi Adeleye, Ruth Laryea, Raelle Tagge, Sunday Adeniyi, Nathaniel Adusei, Wisdom Oguike, Paul Olowoyo, Olayinka Adebajo, Abimbola Olalere, Olayinka Oladele, Joseph Yaria, Bimbo Fawale, Philip Ibinaye, Olalekan Oyinloye, Yaw Mensah, Omotola Oladimeji, Josephine Akpalu, Benedict Calys-Tagoe, Hamisu A. Dambatta, Adesola Ogunniyi, Rajesh Kalaria, Donna Arnett, Charles Rotimi, Bruce Ovbiagele, Mayowa O. Owolabi, for the SIREN Team
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2024-02-01
Reeks:	Genome Medicine
Onderwerpen:	Stroke Genomics GWAS African ancestry, Ischemic stroke, SNP, miRNA
Online toegang:	https://doi.org/10.1186/s13073-023-01273-5
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