Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli

Abstract Bacterial meningitis remains a leading cause of infection-related mortality worldwide. Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the underlying mechanisms governing bacterial blood-brain barrier (BBB) disruption during infection remain elusive....

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Detalhes bibliográficos

Principais autores:	Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen, Xiangru Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-01-01
coleção:	Cell Communication and Signaling
Assuntos:	Meningitic E. Coli Blood-brain barrier Early growth response 1 Permeability Neuroinflammation
Acesso em linha:	https://doi.org/10.1186/s12964-024-01488-y
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