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Comparative Analysis of Anticoagulation Stability in Critically Ill Patients Receiving Argatroban for Suspected or Confirmed Heparin-Induced Thrombocytopenia Compared with Unfractionated Heparin: A Retrospective Cohort Study

<b>Background:</b> Achieving and maintaining therapeutic anticoagulation with unfractionated heparin in critically ill patients is challenging due to biologic variability, heparin resistance, and limitations of activated partial thromboplastin time (aPTT) monitoring. Argatroban, a direct thrombin in...

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Hlavní autoři: Imran Khan, Elizabeth Lamarche, Bernadett Kovacs, Ariel Hendin, Andy Pan, Caitlin Richler, Christine Landry, Sydney Morin, Kaouther Derouiche, Pierre Thabet
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2026-04-01
Edice:Hematology Reports
Témata:
argatroban
unfractionated heparin
time in therapeutic range
aPTT
heparin resistance
heparin-induced thrombocytopenia
On-line přístup:https://www.mdpi.com/2038-8330/18/3/31
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