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Urothelial genotoxicity of household chemicals in healthy canine urinary bladder organoids relative to observed urinary exposures in pet dogs

IntroductionUrothelial carcinoma (UC) in pet dogs closely resembles human muscle-invasive UC, which is associated with environmental chemical carcinogens. The aim of this study was to determine whether urinary concentrations of the bladder carcinogens acrolein, inorganic arsenic, and 2,6-dimethylani...

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Principais autores: Hannah M. Peterson, Christopher Zdyrski, Karin Allenspach, Jonathan P. Mochel, Lauren A. Trepanier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-12-01
coleção:Frontiers in Veterinary Science
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fvets.2025.1702980/full
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