TLR22-Induced Pro-Apoptotic mtROS Abets UPRmt-Mediated Mitochondrial Fission in Aeromonas hydrophila-Infected Headkidney Macrophages of Clarias gariepinus

Toll-like receptors (TLRs) are epitomized as the first line of defense against pathogens. Amongst TLRs, TLR22 is expressed in non-mammalian aquatic vertebrates, including fish. Using headkidney macrophages (HKM) of Clarias gariepinus, we reported the pro-apoptotic and microbicidal role of TLR22 in A...

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Principais autores:	Manmohan Kumar, Shagun Sharma, Munira Haque, Jai Kumar, Umesh Prasad Sah Hathi, Shibnath Mazumder
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-07-01
Serija:	Frontiers in Immunology
Teme:	A. hydrophila TLR22 mtROS UPRmt mitochondrial fission apoptosis
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.931021/full
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