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The impact of ACE2 polymorphisms (rs1978124, rs2285666, and rs2074192) and ACE1 rs1799752 in the mortality rate of COVID-19 in different SARS-CoV-2 variants

Abstract Background Clinical severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes could be influenced by genetic polymorphisms in angiotensin I-converting enzyme (ACE1) and ACE2. This study aims to examine three polymorphisms (rs1978124, rs2285666, and rs2074192) on the...

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Principais autores: Farzaneh Sheikhian, Sahar Sadeghi Mofrad, Samira Tarashi, Morteza Ghazanfari Jajin, Fatemeh Sakhaee, Iraj Ahmadi, Enayat Anvari, Mojgan Sheikhpour, Abolfazl Fateh
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-06-01
coleção:Human Genomics
Assuntos:
SARS-CoV-2 variants
COVID-19
ACE2 polymorphisms
ACE1 rs1799752
Acesso em linha:https://doi.org/10.1186/s40246-023-00501-8
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