T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing

BackgroundHepatocellular carcinoma (HCC), the third most prevalent cause of cancer-related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T-cell depletion (TEX) is a progressive decline in T-cell function due to continuous stimulation of the TCR in the presenc...

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Detaylı Bibliyografya
Asıl Yazarlar:	Hao Chi, Songyun Zhao, Jinyan Yang, Xinrui Gao, Gaoge Peng, Jinhao Zhang, Xixi Xie, Guobin Song, Ke Xu, Zhijia Xia, Shi Chen, Jinqiu Zhao
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2023-03-01
Seri Bilgileri:	Frontiers in Immunology
Konular:	T-cell exhaustion HCC single-cell RNA-seq machine learning tumor microenvironment immunotherapy
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1137025/full
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T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing

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