Neuroglial P2Y1 receptor signalling differentially contributes to inflammatory neurodegeneration

Abstract Extracellular adenosine triphosphate (ATP) and diphosphate (ADP) act as key signalling molecules in the central nervous system (CNS) and regulate neuroinflammatory responses through purinergic receptors. Although astrocytes and neurons undergo profound changes in signalling and metabolism d...

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Bibliographic Details

Main Authors:	Charlotte Schubert, Ricardo Lopes Fonseca, Alexandros Hadjilaou, Vanessa Vieira, Karoline Degenhardt, Anna Lena Seemann, Alice Hakimy, Jana K. Sonner, Peter Ludewig, Tim Magnus, Marion Schneider, Christa E. Müller, Daniela Hirnet, Manuel A. Friese
Format:	Artigo
Language:	Inglês
Published:	BMC 2026-06-01
Series:	Journal of Neuroinflammation
Subjects:	EAE Neuroinflammation Neuron-glial crosstalk Adenine nucleotides Purine receptors
Online Access:	https://doi.org/10.1186/s12974-026-03904-1
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