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CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta

Tissue insults in response to inflammation, hypoxia and ischemia are accompanied by the release of ATP into the extracellular space. There, ATP modulates several pathological processes, including chemotaxis, inflammasome induction and platelet activation. ATP hydrolysis is significantly enhanced in...

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Главные авторы: Désirée Forstner, Jacqueline Guettler, Beatrice A. Brugger, Freya Lyssy, Lena Neuper, Christine Daxboeck, Gerhard Cvirn, Julia Fuchs, Kristin Kraeker, Alina Frolova, Daniela S. Valdes, Christina Stern, Birgit Hirschmugl, Herbert Fluhr, Christian Wadsack, Berthold Huppertz, Olivia Nonn, Florian Herse, Martin Gauster
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2023-05-01
Серии:Frontiers in Cell and Developmental Biology
Предметы:
ectonucleotidases
placenta
platelet-derived factors
adenosine triphosphate (ATP)
preecclampsia
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fcell.2023.1183793/full
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