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Genetically engineered stem cell-derived retinal grafts for improved retinal reconstruction after transplantation

Summary: ESC/iPSC-retinal sheet transplantation, which supplies photoreceptors as well as other retinal cells, has been shown to be able to restore visual function in mice with end-stage retinal degeneration. Here, by introducing a novel type of genetically engineered mouse ESC/iPSC-retinal sheet wi...

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Principais autores: Take Matsuyama, Hung-Ya Tu, Jianan Sun, Tomoyo Hashiguchi, Ryutaro Akiba, Junki Sho, Momo Fujii, Akishi Onishi, Masayo Takahashi, Michiko Mandai
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-08-01
Serier:iScience
Fag:
Neuroscience
Cellular neuroscience
Bioengineering
Tissue engineering
Stem cells research
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004221008348
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