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Study on the Synthesis, Biological Activity and Spectroscopy of Naphthalimide-Diamine Conjugates

Eleven novel naphthalimide-diamine conjugates were synthesized and their structures were confirmed by elemental analysis, 1H-NMR, 13C-NMR and MS. Their in vitro antitumor activities were assessed using MTT assays on two cancerous cell lines K562, HCT116, and one normal hepatoma cell line QSG 7701. C...

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Principais autores: Zhi-Yong Tian, Jing-Hua Li, Qian Li, Feng-Lei Zang, Zhong-Hua Zhao, Chao-Jie Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-06-01
coleção:Molecules
Assuntos:
naphthalimide
diamine conjugates
synthesis
antitumor activity
spectroscopy
Acesso em linha:http://www.mdpi.com/1420-3049/19/6/7646
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