Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring. This study aimed to conduct a population pharmacokinetics (PPK) analysis of lithium and investigate the appropriateness...

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Detalhes bibliográficos

Principais autores:	Zi-bin Jin, Zhuo Wu, Yi-fan Cui, Xue-peng Liu, Hong-bo Liang, Jia-yong You, Chen-yu Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-07-01
coleção:	Frontiers in Pharmacology
Assuntos:	lithium bipolar disorder population pharmacokinetics Monte Carlo simulation dosage regimen
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2022.913935/full
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