Green and sustainable LC-APCI-MS/MS method for simultaneous quantification of genotoxic nitrosamines in antidiabetic medication: sitagliptin

Abstract The International Agency for Research on Cancer categorized nitrosamines as potential or probable human carcinogens. Hence, nitrosamine impurities should be controlled to minimize the cancer risk. Sustainable Development Goal 9 (SDG9: Industry, Innovation, and Infrastructure), Target 9.4 wa...

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Principais autores:	Sriram Pepakayala, Venkata Nadh Ratnakaram, Yuvaraj Zunjarrao, Yogesh Kumar Lohia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-05-01
coleção:	BMC Chemistry
Assuntos:	Nitrosamines Genotoxic impurities LC–MS/MS Method development Multiple reaction monitoring Validation
Acesso em linha:	https://doi.org/10.1186/s13065-025-01503-4
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