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HIV-1 envelope glycoprotein variable loops are indispensable for envelope structural integrity and virus entry.

HIV-1 envelope (Env) glycoprotein is a trimer of heterodimer of gp120 and gp41, and derives from a trimeric glycoprotein precursor, gp160. Gp120 contains five conserved regions that are interspersed with 5 variable loop regions (V1-V5). Env variations in variable loop length and amino acid compositi...

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Autors principals: Tingting Yuan, Jingjing Li, Mei-Yun Zhang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3731308?pdf=render
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