CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons

Cystic fibrosis (CF) is an inherited disorder caused by biallelic mutations of the CF transmembrane conductance regulator (CFTR) gene. Converging evidence suggests that CF carriers with only 1 defective CFTR copy are at increased risk for CF-related conditions and pulmonary infections, but the molec...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xi Zhang, Camille M. Moore, Laura D. Harmacek, Joanne Domenico, Vittobai Rashika Rangaraj, Justin E. Ideozu, Jennifer R. Knapp, Katherine J. Woods, Stephanie Jump, Shuang Jia, Jeremy W. Prokop, Russell Bowler, Martin J. Hessner, Erwin W. Gelfand, Hara Levy
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Clinical investigation 2022-03-01
Цуврал:	JCI Insight
Нөхцлүүд:	Pulmonology
Онлайн хандалт:	https://doi.org/10.1172/jci.insight.152186
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!