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Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses

ABSTRACTWe previously identified the bisbenzimide Hoechst 33342 (H42) as a potent multi-stage inhibitor of the prototypic poxvirus, the vaccinia virus (VACV), and several parapoxviruses. A recent report showed that novel bisbenzimide compounds similar in structure to H42 could prevent human cytomega...

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Principais autores: Jerzy Samolej, Diogo Correa Mendonca, Nicole Upfold, Marion McElwee, Mariann Landsberger, Artur Yakimovich, Arvind H. Patel, Blair L. Strang, Jason Mercer
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2024-04-01
Serija:Microbiology Spectrum
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Online dostop:https://journals.asm.org/doi/10.1128/spectrum.04072-23
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