A mitoxyperilysis-related signature stratifies prognosis and identifies an aggressive colorectal cancer ecosystem with immune remodeling

BackgroundMitoxyperilysis is a recently described lytic cell death pathway linked to innate immune activation and metabolic disruption. Its clinical and biological relevance in colorectal cancer (CRC) remains unclear. This study aimed to develop a mitoxyperilysis-related signature (MRS) for prognost...

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Hlavní autoři:	Yi Zhang, Bin Sun, Joshua Lin, Chengsheng Ding, Xueliang Zhou, Ximo Xu, Kefan Dai, Xiaodong Fan, Man Lu, Zirui He, Xiao Yang, Minhua Zheng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-07-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	artificial intelligence cancer ecosystem state cell-cell communication colorectal cancer machine learning mitoxyperilysis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1851988/full
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