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Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases

DNA replication licensing occurs on chromatin, but how the chromatin template is regulated for replication remains mostly unclear. Here, we have analyzed the requirement of histone methyltransferases for a specific type of replication: the DNA re-replication induced by the downregulation of either G...

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Detalhes bibliográficos
Principais autores: Fei Lu, Xiaojun Wu, Feng Yin, Christina Chia-Fang Lee, Min Yu, Ivailo S. Mihaylov, Jiekai Yu, Hong Sun, Hui Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2016-10-01
coleção:Biology Open
Assuntos:
Acesso em linha:http://bio.biologists.org/content/5/10/1449
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