Induction of Identical IgG HIV-1 Envelope Epitope Recognition Patterns After Initial HIVIS-DNA/MVA-CMDR Immunization and a Late MVA-CMDR Boost

In the RV144 trial, to date the only HIV-1 vaccine efficacy trial demonstrating a modestly reduced risk of HIV-1 acquisition, antibody responses toward the HIV Envelope protein (Env) variable (V) 2 and V3 regions were shown to be correlated with a reduced risk of infection. These potentially protect...

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主要な著者:	Agricola Joachim, Mohamed I. M. Ahmed, Georgios Pollakis, Lisa Rogers, Verena S. Hoffmann, Patricia Munseri, Said Aboud, Eligius F. Lyamuya, Muhammad Bakari, Merlin L. Robb, Britta Wahren, Eric Sandstrom, Charlotta Nilsson, Gunnel Biberfeld, Christof Geldmacher, Kathrin Held
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2020-04-01
シリーズ:	Frontiers in Immunology
主題:	human immunodeficiency virus 1 (HIV-1) vaccine envelope (Env) envelope-specific antibody response epitope variants immunogen structure
オンライン･アクセス:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00719/full
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