Association between Polygenic Risk Score and One-Year Outcomes Following As-Needed Aflibercept Therapy for Exudative Age-Related Macular Degeneration

We investigated whether polygenic risk score (PRS) was associated with one-year outcome of as-needed aflibercept therapy for exudative age-related macular degeneration (AMD), including AMD (<i>n</i> = 129) and polypoidal choroidal vasculopathy (<i>n</i> = 132). A total of 261 patients were treated w...

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Detalhes bibliográficos

Principais autores:	Taiyo Shijo, Yoichi Sakurada, Seigo Yoneyama, Wataru Kikushima, Atsushi Sugiyama, Mio Matsubara, Yoshiko Fukuda, Fumihiko Mabuchi, Kenji Kashiwagi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-09-01
coleção:	Pharmaceuticals
Assuntos:	age-related macular degeneration polygenic risk score aflibercept therapy treatment outcomes <i>ARMS2</i> <i>CFH</i>
Acesso em linha:	https://www.mdpi.com/1424-8247/13/9/257
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