Metastatic lymph node targeted CTLA4 blockade: a potent intervention for local and distant metastases with minimal ICI-induced pneumonia
Abstract Background Immune checkpoint blockade (ICB) elicits a strong and durable therapeutic response, but its application is limited by disparate responses and its associated immune-related adverse events (irAEs). Previously, in a murine model of lymph node (LN) metastasis, we showed that intranod...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2023-06-01
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| Серии: | Journal of Experimental & Clinical Cancer Research |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1186/s13046-023-02645-w |
| Метки: |
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