BARD1 mystery: tumor suppressors are cancer susceptibility genes

Abstract The full-length BRCA1-associated RING domain 1 (BARD1) gene encodes a 777-aa protein. BARD1 displays a dual role in cancer development and progression as it acts as a tumor suppressor and an oncogene. Structurally, BARD1 has homologous domains to BRCA1 that aid their heterodimer interaction...

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Autores principales:	Yousef M. Hawsawi, Anwar Shams, Abdulrahman Theyab, Wed A. Abdali, Nahed A. Hussien, Hanan E. Alatwi, Othman R. Alzahrani, Atif Abdulwahab A. Oyouni, Ahmad O. Babalghith, Mousa Alreshidi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2022-06-01
Colección:	BMC Cancer
Materias:	BARD1 Breast Cancer Tumor suppressor Oncogene
Acceso en línea:	https://doi.org/10.1186/s12885-022-09567-4
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