Modeling Parkinson's disease‐related symptoms in alpha‐synuclein overexpressing mice

Abstract Background Intracellular deposition of alpha‐synuclein (α‐syn) as Lewy bodies and Lewy neurites is a central event in the pathogenesis of Parkinson's disease (PD) and other α‐synucleinopathies. Transgenic mouse models overexpressing human α‐syn, are useful research tools in preclinical stud...

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Autors principals:	Agata Aniszewska, Joakim Bergström, Martin Ingelsson, Sara Ekmark‐Lewén
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2022-07-01
Col·lecció:	Brain and Behavior
Matèries:	alpha‐synuclein behavioral test ethology Parkinson´s disease transgenic mouse models translational research
Accés en línia:	https://doi.org/10.1002/brb3.2628
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