Prevention and control of chicken coccidiosis construction of recombinant Lactococcus lactis expressing chicken IL-4 and IL-2 fusion protein and its immune synergistic effect on chicken coccidia live vaccine

ABSTRACT: Intestinal mucosa injury and loss of weight gain are unavoidable while using live vaccine strain to prevent chicken coccidiosis. In this study, recombinant Lactococcus lactis NZ3900/pNZ8149-IL-4-IL-2, expressing the fusion protein of chicken IL-4 and IL-2, was constructed using food-grade...

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Egile Nagusiak:	Longlong Zheng, Li Zhang, Fan Tan, Chen Wang, Xiaoling Lv, Rui Bai, Nairui Huo, Mingxue Zheng
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2023-04-01
Saila:	Poultry Science
Gaiak:	recombinant L. lactis NZ3900/pNZ8149-IL-4-IL-2 coccidiosis live vaccine immune adjuvant immune synergism
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S0032579123000548
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