Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2α and altered expression of iron absorption genes in mice.

Iron and copper are essential trace metals, actively absorbed from the proximal gut in a regulated fashion. Depletion of either metal can lead to anemia. In the gut, copper deficiency can affect iron absorption through modulating the activity of hephaestin - a multi-copper oxidase required for optim...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Pavle Matak, Sara Zumerle, Maria Mastrogiannaki, Souleiman El Balkhi, Stephanie Delga, Jacques R R Mathieu, François Canonne-Hergaux, Joel Poupon, Paul A Sharp, Sophie Vaulont, Carole Peyssonnaux
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Public Library of Science (PLoS) 2013-01-01
Cyfres:	PLoS ONE
Mynediad Ar-lein:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0059538&type=printable
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!