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Striatal spine plasticity in Parkinson's Disease

Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson’s disease (PD). In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic term...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Rosa M Villalba, Yoland eSmith
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2010-12-01
Sraith:Frontiers in Neuroanatomy
Ábhair:
Rochtain ar líne:http://journal.frontiersin.org/Journal/10.3389/fnana.2010.00133/full
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