Structural Evaluation and Conformational Dynamics of <i>ZNF141^T474I</i> Mutation Provoking Postaxial Polydactyly Type A

Postaxial Polydactyly (PAP) is a congenital disorder of limb abnormalities characterized by posterior extra digits. Mutations in the N-terminal region of the Zinc finger protein 141 (<i>ZNF141)</i> gene were recently linked with PAP type A. Zinc finger proteins exhibit similarity at their N-terminal...

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Hlavní autoři:	Yasir Ali, Faisal Ahmad, Muhammad Farhat Ullah, Noor Ul Haq, M. Inam Ul Haq, Abdul Aziz, Ferjeni Zouidi, M. Ijaz Khan, Sayed M. Eldin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-12-01
Edice:	Bioengineering
Témata:	<i>ZNF141</i> gene point mutation molecular dynamics simulations non-synonymous SNPs postaxial polydactyly
On-line přístup:	https://www.mdpi.com/2306-5354/9/12/749
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