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The Potential Role of Coagulation Factor Xa in the Pathophysiology of COVID-19: A Role for Anticoagulants as Multimodal Therapeutic Agents

SARS-CoV-2 infection (COVID-19) results in local and systemic activation of inflammation and coagulation. In this review article, we will discuss the potential role of coagulation factor Xa (FXa) in the pathophysiology of COVID-19. FXa, a serine protease, has been shown to play a role in the cleavag...

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Principais autores: Galit H. Frydman, Michael B. Streiff, Jean M. Connors, Gregory Piazza
Format: Artigo
Sprog:Inglês
Udgivet: Georg Thieme Verlag KG 2020-10-01
Serier:TH Open
Fag:
sars-cov-2
coronavirus
covid-19
coagulation
factor x
factor xa
anticoagulants
Online adgang:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1718415
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