Brain health and the gut microbiome (bMicrobiome Study): a proof-of-concept, feasibility study integrating shotgun metagenomics, metrology, and multidimensional phenotyping across the cognitive aging spectrum

Background Associations between the gut microbiome and cognitive decline remain inconsistent, reflecting methodological variability, small cohorts, and limited integration of behavioral and lifestyle factors. The microbiota–gut–brain axis may influence cognition through metabolic, immune, and neuroe...

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Principais autores:	Leigh A. Frame, Alison Warren, Abdelmohsen Al Qalam, Patrick G. Corr, Mina Farah, Michaela Karam, Katherine Rangoussis, Mehrshad Fahim Devin, Zeynep Celikkol, Lindsey Gordon, Daniel Villarreal, Elizabeth Catto, Yvonne Udam, Katherine Thompson, Owen Lubinski, Abdallah Samman, Alia Badawi, Holly Hack, Monique Hunter, Ian Hines, Stephanie Servetas, Scott A. Jackson, Nur A. Hasan, Mikhail Kogan
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis Group 2026-12-01
Serija:	Gut Microbes Reports
Teme:	Gut microbiome cognitive aging mild cognitive impairment Alzheimer's disease gut–brain axis shotgun metagenomics
Online dostop:	https://www.tandfonline.com/doi/10.1080/29933935.2026.2679810
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