Use of Transient Transfection for cGMP Manufacturing of eOD-GT8 60mer, a Self-Assembling Nanoparticle Germline-Targeting HIV-1 Vaccine Candidate

We describe the current Good Manufacturing Practice (cGMP) production and subsequent characterization of eOD-GT8 60mer, a glycosylated self-assembling nanoparticle HIV-1 vaccine candidate and germline targeting priming immunogen. Production was carried out via transient expression in the human embry...

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Auteurs principaux:	Vaneet K. Sharma, Sergey Menis, Evan T. Brower, Eddy Sayeed, Jim Ackland, Angela Lombardo, Christopher A. Cottrell, Jonathan L. Torres, Thomas Hassell, Andrew B. Ward, Vadim Tsvetnitsky, William R. Schief
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2024-05-01
Collection:	Pharmaceutics
Sujets:	transient transfection cGMP self-assembling nanoparticle vaccine HIV vaccine
Accès en ligne:	https://www.mdpi.com/1999-4923/16/6/742
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