Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Abstract Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface. Importantly, OMVs can cross the intestinal epithelia...

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Detalhes bibliográficos

Principais autores:	Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-06-01
Colecção:	Microbiome
Assuntos:	Dendritic cells Outer membrane vesicles Bacteroides thetaiotaomicron Interleukin-10 Inflammatory bowel disease
Acesso em linha:	http://link.springer.com/article/10.1186/s40168-020-00868-z
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