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Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis.

Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating their orientation on the spindle at meiosis I. Fo...

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Autors principals: Michel F Guiraldelli, Craig Eyster, Joseph L Wilkerson, Michael E Dresser, Roberto J Pezza
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-03-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC3605105?pdf=render
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