SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation

The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim). Since cellular replication protein A (RPA) prevents primase from starting RNA synthesis on...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Nichodemus O. Onwubiko, Felicia Scheffel, Ingrid Tessmer, Heinz Peter Nasheuer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-03-01
coleção:	FEBS Open Bio
Assuntos:	DNA polymerase α‐primase (Pol α) eukaryotic DNA replication initiation reaction Okazaki fragment synthesis replication protein A (RPA) SV40 large T antigen
Acesso em linha:	https://doi.org/10.1002/2211-5463.13373
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!