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Inhibition of murine herpesvirus-68 replication by IFN-gamma in macrophages is counteracted by the induction of SOCS1 expression.

Gamma interferon (IFN-γ) is known to negatively regulate murine gammaherpesvirus-68 (MHV-68 or γHV-68) replication. This process involves the suppression of the viral gene replication and transcription activator (RTA) promoter, as well as activation of signal transducers and activators of transcript...

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Autors principals: Yong Shen, Saisai Wang, Fangfang Sun, Gang Zheng, Tingting Wu, Yushen Du, Suzhan Zhang, Jing Qian, Ren Sun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-08-01
Col·lecció:PLoS Pathogens
Accés en línia:http://europepmc.org/articles/PMC6093694?pdf=render
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