Chemoproteomics-based profiling elucidates the antimalarial effects of amodiaquine through disruption of glycolysis process in Plasmodium falciparum

Abstract Background Malaria poses a significant global health threat, and 4-aminoquinolines have played a pivotal role in the decades-long fight against malaria. Amodiaquine (AQ), a prominent member of the class, has been employed clinically for decades and, in combination with artesunate (AS), cons...

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Päätekijät:	Jianyou Wang, Chen Wang, Ruishen Zhuge, Huan Tang, Fei Xia, Ying Zhang, Junzhe Zhang, Cui Liu, Jiao Wu, Xiao Chen, Peng Gao, Jigang Wang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2026-01-01
Sarja:	Cell Communication and Signaling
Aiheet:	Amodiaquine Antimalaria ABPP Glycolysis
Linkit:	https://doi.org/10.1186/s12964-026-02663-z
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