Clinical roles of EGFR amplification in diffuse gliomas: a real-world study using the 2021 WHO classification of CNS tumors

BackgroundThe 2021 World Health Organization Classification of Central Nervous System Tumors updates glioma subtyping and grading system, and incorporates EGFR amplification (Amp) as one of diagnostic markers for glioblastoma (GBM).PurposeThis study aimed to describe the frequency, clinical value an...

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Hauptverfasser:	Hai Wang, Xin Zhang, Jiahui Liu, Wenlin Chen, Xiaopeng Guo, Yaning Wang, Yuekun Wang, Hao Xing, Tingyu Liang, Yixin Shi, Delin Liu, Tianrui Yang, Yu Xia, Junlin Li, Jiaming Wu, Qianshu Liu, Tian Qu, Siying Guo, Huanzhang Li, Kun Zhang, Yilin Li, Shanmu Jin, Dachun Zhao, Yu Wang, Wenbin Ma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-02-01
Schriftenreihe:	Frontiers in Neuroscience
Schlagworte:	diffuse gliomas 2021 WHO classification of central nervous system tumors EGFR amplification integrated diagnosis glioblastoma
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1308627/full
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