Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth

Glioblastoma (GBM, WHO grade IV glioma) is the most common and lethal malignant brain tumor in adults with a dismal prognosis. The extracellular matrix (ECM) supports GBM progression by promoting tumor cell proliferation, migration, and immune escape. Uridine diphosphate (UDP)-glucose 6-dehydrogenas...

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Bibliografische gegevens

Hoofdauteurs:	Daqian Zhan, Fatih Yalcin, Ding Ma, Yi Fu, Shuang Wei, Bachchu Lal, Yunqing Li, Omar Dzaye, John Laterra, Mingyao Ying, Hernando Lopez-Bertoni, Shuli Xia
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	KeAi Communications Co., Ltd. 2022-05-01
Reeks:	Genes and Diseases
Onderwerpen:	4-MU Extracellular matrix (ECM) Glioblastoma (GBM) Hyaluronic acid (HA) Phagocytosis T cells
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2352304221001057
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