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Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity

<p>Abstract</p> <p>Background</p> <p>The Tousled Like Kinases (TLKs) are involved in chromatin dynamics, including DNA replication and repair, transcription, and chromosome segregation. Indeed, the first two TLK1 substrates were identified as the histone H3 and Asf1 (a histone H3/H4 chaperone), whic...

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Autore principale: De Benedetti Arrigo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2010-03-01
Serie:BMC Research Notes
Accesso online:http://www.biomedcentral.com/1756-0500/3/68
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