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Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of Ascaris reveals a novel fold and two discrete lipid-binding sites.

Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins found only in nematodes. They are synthesized as large, tandemly repetitive polyproteins that are post-translationally cleaved into multiple copies of small lipid binding proteins with virtually identical fatty acid...

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Detalhes bibliográficos
Principais autores: Nicola A G Meenan, Graeme Ball, Krystyna Bromek, Dušan Uhrín, Alan Cooper, Malcolm W Kennedy, Brian O Smith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-04-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC3079579?pdf=render
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