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Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin

Growth factors, such as insulin, can induce both acute and long-term glucose uptake into cells. Apart from the rapid, insulin-induced fusion of glucose transporter (GLUT)4 storage vesicles with the cell surface that occurs in muscle and adipose tissues, the mechanism behind acute induction has been...

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Главные авторы: Althea N. Waldhart, Holly Dykstra, Anderson S. Peck, Elissa A. Boguslawski, Zachary B. Madaj, Jennifer Wen, Kelsey Veldkamp, Matthew Hollowell, Bin Zheng, Lewis C. Cantley, Timothy E. McGraw, Ning Wu
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017-06-01
Серии:Cell Reports
Предметы:
GLUT4
TXNIP
insulin
AKT
glucose
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2211124717306836
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