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Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.

CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03) and hypothesised that Kras may regulate Cten. To...

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Huvudupphov: Saleh Al-Ghamdi, Abdulkader Albasri, Julien Cachat, Salih Ibrahem, Belal A Muhammad, Darryl Jackson, Abdolrahman S Nateri, Karin B Kindle, Mohammad Ilyas
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Länkar:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0020919&type=printable
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